- Fat-rich fluid fuels immune failure in ovarian cancer
New research has uncovered how lipid-rich fluid in the abdomen, known as ascites, plays a central role in weakening the body's immune response in advanced ovarian cancer. The findings offer new insights into immune suppression in ovarian cancer and open promising avenues for future immunotherapy approaches. Over 70% of patients with ovarian cancer are diagnosed at an advanced stage, often presenting with large volumes of ascites. This ascites fluid not only supports the spread of cancer througho…
- 2 days ago 10 May 25, 1:12am -
- The origins of language
Wild chimpanzees alter the meaning of single calls when embedding them into diverse call combinations, mirroring linguistic operations in human language. Human language, however, allows an infinite generation of meaning by combining phonemes into words and words into sentences. This contrasts with the very few meaningful combinations reported in animals, leaving the mystery of human language evolution unresolved.
- 2 days ago 10 May 25, 1:12am -
- Antibiotics from human use are contaminating rivers worldwide, study shows
Millions of kilometers of rivers around the world are carrying antibiotic pollution at levels high enough to promote drug resistance and harm aquatic life, a new study warns. The study estimated the scale of global river contamination from human antibiotics use. Researchers calculated that about 8,500 tons of antibiotics -- nearly one-third of what people consume annually -- end up in river systems around the world each year even after in many cases passing through wastewater systems.
- 2 days ago 9 May 25, 10:52pm -
- A more realistic look at DNA in action
By creating a more true-to-life representation of DNA's environment, researchers have discovered that strand separation may take more mechanical force than the field previously believed.
- 2 days ago 9 May 25, 10:52pm -
- Novel, needle-free, live-attenuated influenza vaccines with broad protection against human and avian virus subtypes
A research team has achieved a significant breakthrough in developing broadly protective, live-attenuated influenza vaccines (LAIV). These innovative LAIV platforms offer potential to develop universal influenza vaccines that induce a more robust immune response against various virus subtypes, including both human and avian strains.
- 2 days ago 9 May 25, 9:52pm -
- Researchers map 7,000-year-old genetic mutation that protects against HIV
Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose -- and how it protected our ancestors from ancient diseases.
- 2 days ago 9 May 25, 9:52pm -
- Colonic inflammation explains missing link between obesity and beta-cell proliferation
How does obesity affect insulin production? Researchers are shining light on new stages of the ERK pathway.
- 2 days ago 9 May 25, 9:52pm -
- An enzyme as key to protein quality
In neurodegenerative diseases such as Alzheimer's or Parkinson's, proteins accumulate in the body's cells, fold incorrectly and clump together to form larger aggregates. Normally, cells are able to remove these aggregates themselves. However, if a certain enzyme is blocked, this clean-up process no longer works. The new findings provide a better understanding of the molecular basis of these processes.
- 2 days ago 9 May 25, 9:51pm -
- Fatty liver in pregnancy may increase risk of preterm birth
Pregnant women with metabolic dysfunction-associated steatotic liver disease (MASLD) have an increased risk of giving birth prematurely and the risk increase cannot be explained by obesity, according to a new study.
- 2 days ago 9 May 25, 9:51pm -
- Improving newborn genetic screening
More than a decade ago, researchers launched the BabySeq Project, a pilot program to return newborn genomic sequencing results to parents and measure the effects on newborn care. Today, over 30 international initiatives are exploring the expansion of newborn screening using genomic sequencing (NBSeq), but a new study highlights the substantial variability in gene selection among those programs.
- 2 days ago 9 May 25, 9:49pm -
- Can frisky flies save human lives?
A scientist decided to find out why a bacterial infection makes fruit flies promiscuous. What he discovered could help curb mosquito-borne diseases and manage crop pests.
- 2 days ago 9 May 25, 9:49pm -
- New gene linked to severe cases of Fanconi anemia
Mutations in FANCX appear to cause a lethal form of Fanconi anemia, a finding that sheds light on unexplained pregnancy loss and offers new avenues for genetic screening.
- 2 days ago 9 May 25, 9:49pm -
- Heart rhythm disorder traced to bacterium lurking in our gums
New research shows that the gum disease bacterium P. gingivalis can slip into the bloodstream and infiltrate the heart. There, it quietly drives scar tissue buildup -- distorting the heart's architecture, disrupting electrical signals, and raising the risk of atrial fibrillation.
- 2 days ago 9 May 25, 9:49pm -
- Green fabrication of hybrid materials as highly sensitive X-ray detectors
New bismuth-based organic-inorganic hybrid materials show exceptional sensitivity and long-term stability as X-ray detectors, significantly more sensitive than commercial X-ray detectors. In addition, these materials can be produced without solvents by ball milling, a mechanochemical synthesis process that is environmentally friendly and scalable. More sensitive detectors would allow for a reduction in the radiation exposure during X-ray examinations.
- 2 days ago 9 May 25, 9:49pm -
- Studies point to redlining as a 'perfect storm' for breast cancer
New research indicates that while the residential segregation policy was outlawed decades ago, it still impacts women's health today.
- 2 days ago 9 May 25, 9:49pm -